Turn Market Chaos Into Your No. 1 Advantage

Don't let market volatility erode your hard-earned savings. Our free gold guide shows you how to turn your 401k into a gold IRA and protect your retirement today.

AstraZeneca Stops Two Lokelma Late-Stage Trials After Evaluating Potential Benefits

Vandana Singh
December 01, 2023

AstraZeneca Plc (NASDAQ:AZNdiscontinued the STABILIZE-CKD and DIALIZE-Outcomes Phase 3 evidence trials for Lokelma (sodium zirconium cyclosilicate). 

The decision was made due to substantially increased enrollment timelines and low event rates, respectively, which made it prohibitive to deliver study results within a timeframe to advance clinical practice meaningfully.

Also Read: FDA Approves AstraZeneca's Truqap/Faslodex Combo Therapy For Breast Cancer, Competes With Gilead's Drug.

STABILIZE-CKD and DIALIZE-Outcomes trials are part of the CRYSTALIZE evidence program, which includes clinical and real-world evidence studies researching the potential benefit of Lokelma in the management of hyperkalemia (HK) across the cardiorenal spectrum.

Hyperkalemia is the medical term that describes a potassium level in blood that's higher than normal. Potassium is a chemical critical to the function of nerve and muscle cells, including in the heart.

The company will work with investigators to ensure the necessary follow-up with patients.

Lokelma is approved for a broad HK patient population in 56 countries worldwide. The decision to discontinue the trials is not due to safety concerns, and the positive benefit-risk of Lokelma does not change in the approved indication.

Price Action: AZN shares closed at $64.59 on Thursday.

Continue Reading...

Popular

Colombia pauses buying Israeli weapons and president calls war in Gaza 'genocide'

BOGOTA, Colombia (AP) — Colombia’s President Gustavo Petro announced Thursday his government is suspending purchases of weapons from Israel after Palestinians say Israeli troops in Gaza, marking an escalation of tensions between both countries over the .

Clark's final regular-season home game to be among priciest tickets in women's college hoops history

IOWA CITY, Iowa (AP) — Caitlin Clark's at Iowa is likely to bring one of the priciest tickets in women's college basketball history.

Oil Surge Predicted...But Are You Ready? - Ad

Do you own oil and gas stocks? Or are you thinking about buying some? If so, you need to see my #1 oil play for 2024. But it's NOT oil stocks, futures, or anything you've likely heard about. Rather, it's an unusual way to potentially bank monthly income from the oil and gas markets.

C3.Ai To Gain From Unprecedented AI Demand, Analyst Sees Over 30% Growth

C3.ai experiences significant growth potential driven by strong demand for AI solutions, with analysts projecting over 30% revenue growth.

EPA to delay rules for some power plants until after November election

WASHINGTON (AP) — The Environmental Protection Agency said Thursday it is delaying planned rules to curb emissions from existing natural gas plants that release harmful air pollutants and contribute to global warming.

Inflation Proof Investments - Ad

Forget stocks. Their value goes down even as price goes up. And real estate... not in this market. The #1 inflation proof investment right now is GOLD. If you want to protect your retirement savings from inflation, this free guide from the #1 rated gold company in the US shows you how.

Celsius Holdings CEO Sees 'Huge Runway Ahead' As Stock Soars To New Highs

Celsius shares are soaring to all-time highs Thursday following the company's quarterly results. Celsius CEO John Fieldly still sees plenty of runway ahead for the energy drink maker.

How GenAI Can Help Find M&A Targets: Private Equity Meets Hi-Tech

Private equity is shifting its approach toward acquiring takeover targets, and then either selling or taking them public.

Multimillionaire Investor: "Hands Down the Most Lucrative Discovery of My Entire Career" - Ad

Peabody Award-winning journalist Bill Tucker sat down with a reclusive multimillionaire trader... 858 miles OUTSIDE of Wall Street... to discuss a revolutionary new trading strategy that involves... One ticker... one trade... every week. The fast-hitting profit potential is extraordinary.

Missouri House passes property tax cut aimed at offsetting surge in vehicle values

JEFFERSON CITY, Mo. (AP) — Missouri residents could see a roughly $138 million tax break under legislation passed Thursday by the House in an attempt to offset a recent surge in local tax collections caused by higher vehicle values.

Canada reimposes a visa requirement on Mexicans

TORONTO (AP) — Canada’s government is reimposing the visa requirements on Mexican nationals visiting Canada, the immigration minister announced Thursday.

How to Profit From the New Boom in Gold - Ad

Gold just passed $2,000/oz and is set for a new bull run in 2024. Now a renowned precious metals expert is sharing his No. 1 way to play it for just $5.

Stericycle Analysts Increase Their Forecasts After Q4 Results

Stericycle, Inc. (NASDAQ: SRCL) reported mixed fourth-quarter financial results on Wednesday.

Why Gold Is Headed Above $3,000 - Ad

Many experts believe gold is headed to $3,000/oz. or even higher. As this rally picks up... most investors will likely run out and buy an ETF, a gold mining stock, or even bullion. But there's actually a much better way to profit from the emerging gold boom (with just $5.)

Jim Cramer Tells Investors To 'Do The Homework' And Look Beyond Earnings Figures: '...Causing People To Make Snap Judgments'

CNBC's Jim Cramer has advised investors to look beyond the numbers in financial reports, saying that the current method of reporting is leading to false judgments.

This Trader Turned $2,708 Into $3.25 Million With Trump-Related MAGA Memecoin

Pseudonymous Erik Stevens, a self-proclaimed "eccentric multi-millionaire," updated his followers on achieving a "1,024X" on MAGA Memecoin (CRYPTO: TRUMP), the

Transform Your 401K with Gold (Free Guide) - Ad

Market volatility could wipe out your 401K overnight. But if you roll that over into a Gold IRA, you could actually grow your wealth instead. Download this free gold guide from America's #1 gold company to take control of your financial future in these uncertain times.

Beyond Meat, Viking Therapeutics, Novavax, Baidu, Tesla: Why These 5 Stocks Are On Investors' Radars Today

The U.S. indices were mixed with the S&P 500 rising by nearly 0.2% to 5,078.18 and the Dow Jones Industrial Average falling by 0.25% to 38,972.41.

Top 4 Health Care Stocks That Are Preparing To Pump This Month

The most oversold stocks in the health care sector presents an opportunity to buy into undervalued companies.

Elon Got This Right... - Ad

Today, a new technology is about to hit with a force even greater than a tidal wave... I'm talking about artificial intelligence, a technology Elon Musk calls: "The most disruptive force in history." It has already started, that's why Eric Fry is issuing an urgent A.I. Code Red today.

The Power of Investing in Real Estate: The Oprah Winfrey Way

Oprah Winfrey is one of the most successful women in the world. She is a media mogul, television personality, actress, author, and philanthropist. Her net worth is estimated to be over $2.6 billion, and she has made her fortune through various business ventures, including television, film, and publishing.

Mark Cuban Thinks Elon Musk's Grok Chatbot Is Right Leaning, While Google's Gemini Is Left Leaning: 'Can Big Tech Actually Field Generative AI'

Billionaire Mark Cuban suggests Elon Musk's xAI's Grok leans "right," while Google's Gemini tends "left," amidst a broader debate on AI models' biases and implications, fueled by concerns raised by Marc Andreessen about big tech's ability to develop generative AI products.

"America's Top Trader" Issues Urgent Warning: A.I. Code Red - Ad

When "America's Top Trader" issues a brand new warning... the smart money pays close attention. Eric just issued what he says is the most urgent warning of his entire career: What's coming next isn't just a stock market thing.

Big-Time Bitcoin Bull Michael Saylor Encourages Followers To Keep Stacking Coins But 'Stay Humble'

Michael Saylor, CEO of MicroStrategy Inc. (NASDAQ:MSTR), posted a message on X, formerly Twitter, on Wednesday, encouraging Bitcoin (CRYPTO: BTC) holders to “Stay Humble. Stack Sats.”

Act by April 14 - Ad

The last of three historically bullish crypto events is expected to happen around April 14. It's only the fourth time in crypto history. The last time, in 2020, certain altcoins exploded. Some as high as 531,735% or even a 953,018% gain. A tiny $100 investment would have returned just short of a million dollars.

Top 4 Financial Stocks Which Could Rescue Your Portfolio This Quarter

The most oversold stocks in the financial sector presents an opportunity to buy into undervalued companies.

Wall Street's Most Accurate Analysts Say Hold These 3 Tech Stocks With Over 3% Dividend Yields

During times of turbulence and uncertainty in the markets, many investors turn to dividend-yielding stocks. These are often companies that have high free cash flows and reward shareholders with a high dividend payout.

Holding NVDA? Read This Now - Ad

NVDA is likely not the best buy for A.I. investors. 50-year Wall Street veteran Marc Chaikin reveals what to buy instead.

Phones are distracting students in class. More states are pressing schools to ban them

SAN FRANCISCO (AP) — In California, a high school teacher complains that students watch Netflix on their phones during class. In Maryland, a chemistry teacher says students use gambling apps to place bets during the school day.

2024 Oil Boom - Ad

There is a much better way to profit from oil in 2024. It's NOT oil stocks, futures, or anything you've likely heard about. In fact, one man used it build a small $1,000 investment into a $100,000 income stream over fifty years.

Wall Street Legend Predicts Dismal 12-Year Stock Returns, Warns FOMO-Fueled Rally Nearing Peak

John Hussman, the president of the Hussman Investment Trust, has cautioned that the current stock market rally, driven by a "fear of missing out", could lead to disappointing long-term results. This could mean a decade or more of poor returns.

Should You Buy Bitcoin in 2024? [Expert's Shocking Answer] - Ad

Bitcoin minted 100,000 millionaires and if you're not one of them, that ship has sailed. But there's another millionaire-minting crypto at our doorstep... research shows this coin could be 20X bigger than Bitcoin by the end of the decade. With crypto starting to heat up again, this could be the perfect time to get in.

Tucker Carlson Fires Back After Jon Stewart's Pot Shot At Russian President Interview, Calls Comedian 'A Tool Of Regime'

Conservative commentator, Tucker Carlson accused comedian Jon Stewart of being "a tool of the regime" after Stewart criticized Carlson's interview with Russian President Vladimir Putin.

Boeing given 90 days by FAA to come up with a plan to improve safety and quality of manufacturing

The Federal Aviation Administration is giving Boeing 90 days to come up with a plan to fix quality problems and meet safety standards for building new planes.

Your Money or Your Privacy? - Ad

The digital dollar might change more than just currency. Its implications for privacy, autonomy, and personal finance are terrifying. If you don't take control of your money and your privacy, you could lose both to a digital dollar.

Trending Now

Information, charts or examples are for illustration and educational purposes only and not for individualized investment management This message contains commercial elements, such as advertising. We only send these offers to those who have opted in to our newsletter. Past performance is not indicative of future results. For these reasons we strongly suggest trading in a DEMO/Simulated account. The information provided by us is for educational and informational purposes only. We make no representations or warranties concerning the products, practices or procedures of any company or entity mentioned or recommended and have not determined if the statements and opinions of the advertiser are accurate, correct or truthful. If you use, act upon or make decisions in reliance on information contained or any external source linked within it, you do so at your own peril and agree to hold us, our officers, directors, shareholders, affiliates and agents without fault.

Copyright trendadvisor.net
Privacy Policy | Terms of Service