This Intercept Stopped the Gold Sector Cold
114.26 g/t over 10.6m. That's not a typo. And it wasn't deep exploration-it was in an active mining zone.
Shares Stats
| Shares Outstanding | 159,040,000 |
| Shares Float | 154,760,000 |
| Shares Short | 14,550,000 |
| Insider Holdings | 83% |
| Institution Holdings | 104.79% |
About Ionis Pharmaceuticals Inc
Ionis Pharmaceuticals, Inc., a commercial-stage biotechnology company, provides RNA-targeted medicines in the United States. The company offers TRYNGOLZA reduces triglyceride levels in adults with familial chylomicronemia syndrome (FCS) and acute pancreatitis; WAINUA for the treatment of the polyneuropathy of hereditary transthyretin-medicated amyloidosis (ATTRv-PN) in adults; and SPINRAZA for pediatric and adult patients with spinal muscular atrophy (SMA). It also provides QALSODY for the treatment of Amyotrophic Lateral Sclerosis (ALS); TEGSEDI for the treatment of ATTRv-PN in adults; and WAYLIVRA for treatment for FCS and familial partial lipodystrophy. It also develops products under Phase 3 clinical trials, such as Olezarsen for patients with hypertriglyceridemia (SHTG) and cardiovascular disease (CVD); Donidalorsen for patients with hereditary angioedema; and Zilganerse, a potential treatment for people with genetically confirmed Alexander disease, as well as ION582 that has completed Phase 2 clinical trial for the potential treatment of AS, a rare genetic neurological disease. In addition, the company develops Eplontersen to degrade mutant and wild-type TTR mRNA through binding to the TTR mRNA; Pelacarsen to inhibit the production of apolipoprotein(a) in the liver to offer a direct approach for reducing lipoprotein(a); Bepirovirsen to inhibit the production of viral proteins associated with hepatitis B virus; Sefaxersen to reduce the production of complement factor B and lower activation of the alternative complement pathway; and Ulefnersen to reduce the production of the fused in sarcoma, as well as other mid-stage pipeline investigational medicines. It has a strategic collaboration with Biogen for the treatment of neurological disorders; and collaboration and license agreement with GSK, AstraZeneca, Novartis, and Roche, as well as with Metagenomi. The company was incorporated in 1989 and is headquartered in Carlsbad, California.
General
| Name | Ionis Pharmaceuticals Inc |
| Ticker | IONS |
| Exchange | NASDAQ |
| Sector | Healthcare |
| Industry | Biotechnology |
| Currency | USD |
| Country | USA |
| Fiscal Year End | December |
| Full Time Employees | 1,069 |
Highlights
| Analyst Target | 56.00 |
| Market Cap | 5,212,500,000 |
| PEG Ratio | 25.70 |
| EBITDA | -460,854,016 |
Financials
| Curr Year EPS Estimate | -2.29 |
| Next Quarter EPS Estimate | -0.87 |
| Profit Margin | -63.77% |
| Operating Margin | -65.71 |
| Return on Assets | -0.11 |
| Return on Equity | -1.19 |
| Revenue | 717.7M |
| Earnings Per Share | -2.99 |
| Revenue Per Share | 4.69 |
| Gross Profit | -181,148,000 |
| Quarterly Revenue Growth | 0.10 |
Valuation
| Forward PE | 90.91 |
| Price/Sales (Trailing 12 Mt.) | 7.47 |
| Price/Book (Most Recent Quarter) | 11.26 |
Earnings
Warren Buffett's Top Stock Picks Now Come With a 15% Income Bonus Through This Fund
A new ETF is offering investors the chance to follow in the footsteps of one of the world's most successful investors and earn income at the same time.
Why Barrick Gold Stock Is Trading Lower
Barrick Gold Corp (NYSE:GOLD) shares are trading lower by 4.5% to $19.08 during Wednesday’s session.
Elon Musk Drops Stunning Bombshell? - Ad
Behind closed doors, Musk revealed a game-changing breakthrough technology that could shake the tech world & crush major companies. Why is no one talking about it? Luckily, we had a man on the inside - watch now to see the details & how to profit!
Canadians put off by Trump's bluster and border arrests are booking far fewer US visits
VANCOUVER, British Columbia (AP) — Diana and Rick Bellamy initially planned to take a Caribbean cruise out of Houston before heading to Laurel, Mississippi, to visit the home of one of their favorite HGTV shows, “Home Town.”
Shiba Inu Burn Rate Skyrockets 2,094%: What Is Going On?
Shiba Inu (CRYPTO: SHIB) has seen a massive spike in burn activity and on-chain growth, fueling speculation of a
"Market Wizard " Thrives on Tariff Turmoil - Ad
Steel. Copper. Semiconductors. Another round of tariffs is rattling Wall Street, triggering panic selling. But history shows these policy moves don't just create losers - they create massive trading opportunities.
US Treasury secretary says trade war with China is not 'sustainable'
WASHINGTON (AP) — U.S. Treasury Secretary said in a Tuesday speech that the ongoing against China is unsustainable and expects a "de-escalation" in the trade war between the world's two largest economies.
UPS to cut 20,000 jobs, close some facilities as it reduces amount of Amazon shipments it handles
UPS is looking to slash about 20,000 jobs and close more than 70 facilities as it drastically reduces the amount of Amazon shipments it handles.
Trump's Crypto Blueprint Unveils This Infrastructure Powerhouse - Ad
One blockchain token sits at the heart of Washington's pro-crypto agenda. Institutions are loading up while it still trades at a discount. Here's how to get in for $3.
60,000 Americans to lose their rental assistance and risk eviction unless Congress acts
Moments after Daniris Espinal walked into her new apartment in Brooklyn, she prayed. In ensuing nights, she would awaken and touch the walls for reassurance — finding in them a relief that turned to tears over her morning coffee.
Tesla, Palantir And Coinbase Are Among Top 11 Large-Cap Gainers Last Week (Apr 21-Apr 25): Are The Others In Your Portfolio?
These large-cap stocks had strong gains last week. Mobileye, ServiceNow, and Microchip saw the biggest jumps, while Tesla and Robinhood also rose.
World Economic Forum: "Arguably the Most Exciting Human Discovery Since Fire" - Ad
Sam Altman, Bill Gates, and Mark Zuckerberg are all investing vast sums of money into a radical technology. According to Bloomberg, this could become 10 times bigger than AI, quantum computing, electric vehicles, cryptocurrencies, and robotics combined. And one stock is at the center of it all.
Take Investment Advice From Shaq — His Fortune Grew Thanks To Charles Barkley and Donuts
Former NBA player Shaquille O'Neal has seen a significant increase in his wealth, quadrupling his net worth through an investment strategy inspired by Amazon's CEO, Jeff Bezos.
Musk defends his work as he prepares to wind down at DOGE but gives hazy answers on future
WASHINGTON (AP) — , preparing to step back from his work leading the , had a request of the reporters gathered at the White House to interview him: Before he would answer any questions, he wanted someone to tell him a joke.
Executive Order 14179 Could Change Social Security Forever - Ad
President Trump's inner circle has a plan that could radically change how Social Security works. In fact, just days after taking office, President Trump signed Executive Order 14179 - giving his team new powers to permanently reset how many key federal agencies work. That reset is now ready to begin... and it's critical you start preparing your money immediately.
China's Chip Breakthrough Without ASML Makes Chamath Palihapitiya Take Stock Of Beijing's 'Formidable' Nature: 'America Can Win If…'
Former Intel executive William Huo highlights China's breakthrough in producing 5nm chips without EUV technology, sparking concerns from Chamath Palihapitiya that the U.S. risks losing its technological edge to China without urgent innovation.
Immigrants working legally in the Texas Panhandle live in limbo under Trump's crackdown
PANHANDLE, Texas (AP) — The truck driver is cutting his lawn on a windy afternoon, in a town so quiet you can take afternoon walks down the middle of Main Street.
You Can Take a Stake in Elon's xAI Before June 1st... - Ad
Elon Musk's private AI firm xAI may have just leapfrogged ChatGPT and Google's Gemini--building what experts call the future of AI. For the first time, you can take a stake starting at $500.
Corporations Will Pour $330 Billion Into Bitcoin By 2029: Bernstein
Investment firm Bernstein expects corporate treasury allocations to drive approximately $330 billion into Bitcoin (CRYPTO: BTC) over the next five years, fueled primarily by public companies adopting Strategy's (NASDAQ:
Trump's AI Education Push, Cramer's AI Stock Optimism, And More: This Week In Artificial Intelligence
Week full of AI news: Trump advocates for AI education, Cramer bullish on AI stocks, Amazon and Nvidia dismiss data center fears, OpenAI's restructuring raises concerns, Nadella's Microsoft introduces AI updates.
No.1 Opportunity for 2025 [Take Action Now!] - Ad
Starlink's potential IPO Could Be the Biggest in History--Silicon Valley insider James Altucher has uncovered a way to profit BEFORE the IPO--with as little as $50. Musk's $180B giant is set to launch--will you miss out? Claim your spot before it's too late.
Mark Zuckerberg Denies Tilt Towards Donald Trump, Says Big Tech Must Work With 'Whoever' Is In Power, Describes Last Decade As 'Painful Maturation Process'
Zuckerberg denies Silicon Valley bias towards Trump, says Meta wants productive relationship with any government.
Buffett Dismisses Rumors Of Stockpiling Cash For Successor Greg Abel: 'I Wouldn't Do Anything Nearly So Noble Just So Greg Could Look Good'
Berkshire Hathaway chief Warren Buffett, has put to rest rumors that he is accumulating a substantial cash reserve for his successor, Greg Abel.Berkshire Hathaway Inc. (NYSE:BRK.A) chief Warren Buffett, has put to rest rumors that he is accumulating a substantial cash reserve for his success
The Most Important "AI Stock" You've Never Heard Of - Ad
The AI revolution is moving faster than anyone expected. But what no one is talking about is the one company AI simply can't exist without. It may be the single most important AI investment, yet most people don't even know its name. For now. The moment Wall Street catches on, this $20 stock could explode.
Nigel Farage takes aim at the UK's dominant parties with hefty gains in local elections
LONDON (AP) — The hard-right party Reform UK led by snatched a seat in Parliament from the governing Labour Party and won hundreds of local council seats from the opposition Conservatives in elections that Farage hailed Friday as a turning point towards ending the two parties' poltiical dominance.
Apple's AI Team Undergoes Major Restructuring Amidst Performance Concerns
Apple Inc. (NASDAQ: AAPL) has embarked on a major overhaul of its artificial intelligence (AI) and machine learning divisions, shifting elements to different departments within the organization.
Nvidia Is About to Shock the World: July 23rd - Ad
Jeff Brown, the tech legend who picked shares of Nvidia in 2016 before they jumped by more than 22,000%, is warning everyone to... Mark this date on your calendar: July 23rd! That's when Nvidia could help send shares of this Elon Musk supplier skyrocketing higher.
Hilton Grand Vacations Stock Climbs On Q1 Earnings, Company Takes Steps To Maintain 'Good Momentum' In Face Of 'Increased Uncertainty'
Hilton Grand Vacations Inc (NYSE:HGV) reported first-quarter financial results ahead of the market open on Thursday. Here's what you need to know from the print.
Over 2 million Ninja-branded pressure cookers are recalled after reports of serious burn injuries
NEW YORK (AP) — SharkNinja is recalling more than 2 million pressure cookers sold in the U.S. and Canada — after consumers reported over 100 burn injuries spanning from a hazard that can cause hot food to spew out.
Biggest Dividend Payout in U.S. History: $1 Trillion up for Grabs! - Ad
Trump just launched a $1 trillion National Investment Fund to replace income taxes and send direct payouts to Americans. You could claim up to $21,307--before the first public checks go out. This is historic. Act now to be first in line.
Trump Wants 'Movies Made In America Again': Here's What Tariffs On Films Could Mean For Disney, Netflix Stock
Donald Trump threatens the movie sector with tariffs on films produced outside of America. Here's what that could mean.
Donald Trump Weighs In on Third-Term Speculation: 'I Don't Know If It's Constitutional'
President Trump said that he expects his presidency to end after the 2028 election.
Elon's Greatest Invention... Hidden in South Memphis? - Ad
Tech legend Jeff Brown recently traveled to the industrial zone of South Memphis to investigate what he believes will be Elon's greatest invention ever... Yes, even bigger than Tesla or SpaceX.
Wall Street CEOs Pull The 'Trump Tariff' Card: Is Macro Fear The New Excuse For Weak Guidance?—Asks Leading Fund Manager
As "macro uncertainty" and "Trump's tariffs" become the go-to scapegoats for CEOs this earnings season, fund manager Gary Black isn't buying it.
Putin Ally Who Unveiled Tesla Cybertruck With Machine Gun Now Says Elon Musk 'Remotely Disabled' The Militarized EV
Elon Musk has been accused by Chechen leader Ramzan Kadyrov of remotely disabling his Cybertruck.
Gold Is Breaking Records. This Stock Hasn't Moved Yet. - Ad
With gold over $3,200, one near-term producer is still trading like a developer. But the mill is running, crews are working underground, and first production is months away.
Treasury Sec Scott Bessent: US Should Be The 'Premier Destination For Digital Assets'
U.S. Treasury Sec. Bessent advocates for American leadership in digital assets and Congress progresses towards solid crypto market structure.
Is Norfolk Southern 'making it right' after Ohio derailment? New lawsuit adds to doubts
Norfolk Southern began making promises to East Palestine, Ohio, soon after its train in February 2023, saying it would after five tank cars of vinyl chloride were intentionally burned, sending up a huge black plume of smoke that spread more toxic chemicals over homes, schools and farms.
This Intercept Stopped the Gold Sector Cold - Ad
114.26 g/t over 10.6m. That's not a typo. And it wasn't deep exploration-it was in an active mining zone.
Bitcoin, Ethereum, Dogecoin Spike Alongside Stocks: Trader Peter Brandt Says BTC On Target To Reach Bull Market Top Of $125,000-$150,000
Leading cryptocurrencies rallied Thursday as investors turned to Bitcoin amid a weak financial climate.
Information, charts or examples are for illustration and educational purposes only and not for individualized investment management This message contains commercial elements, such as advertising. We only send these offers to those who have opted in to our newsletter. Past performance is not indicative of future results. For these reasons we strongly suggest trading in a DEMO/Simulated account. The information provided by us is for educational and informational purposes only. We make no representations or warranties concerning the products, practices or procedures of any company or entity mentioned or recommended and have not determined if the statements and opinions of the advertiser are accurate, correct or truthful. If you use, act upon or make decisions in reliance on information contained or any external source linked within it, you do so at your own peril and agree to hold us, our officers, directors, shareholders, affiliates and agents without fault.