America's Defense Future Starts Underground
A N. American metals project just caught the attention of Rio Tinto - a mining giant. With four projects in key regions, this firm is aligned with Washington's push to rebuild the defense-metal supply chain.
Shares Stats
| Shares Outstanding | 146,630,000 |
| Shares Float | 131,420,000 |
| Shares Short | 13,110,000 |
| Insider Holdings | 980% |
| Institution Holdings | 101.37% |
About Denali Therapeutics Inc
Denali Therapeutics Inc., a biopharmaceutical company, discovers and develops therapeutics to treat neurodegenerative and lysosomal storage diseases. The company develops Eclitasertib (SAR443122/DNL758) RIPK1 inhibitor program for peripheral inflammatory diseases; DNL343 eIF2B activator program for amyotrophic lateral sclerosis; BIIB122/DNL151 LRRK2 inhibitor program for Parkinson's disease; TAK-594/DNL593 program for frontotemporal dementia-granulin; DNL126 program for MPS IIIA (Sanfilippo Syndrome A); and DNL310 Tividenofusp alfa, an enzyme replacement therapy program for MPS II (Hunter Syndrome). Its Enzyme TransportVehicle (TV) programs include DNL952 for the treatment of Pompe disease; DNL111 for Parkinson's and Gaucher diseases; and DNL622 for Hurler syndrome (MPS I). The company's OTV programs also comprise DNL628 targeting tau for Alzheimer's disease; and DNL422 targeting alpha synuclein for Parkinson's disease, as well as antibody TV program includes DNL921 targeting Abeta for treating Alzheimer's disease. The company was formerly known as SPR Pharma Inc. and changed its name to Denali Therapeutics Inc. in March 2015. Denali Therapeutics Inc. was incorporated in 2013 and is headquartered in South San Francisco, California.
General
| Name | Denali Therapeutics Inc |
| Ticker | DNLI |
| Exchange | NASDAQ |
| Sector | Healthcare |
| Industry | Biotechnology |
| Currency | USD |
| Country | USA |
| Fiscal Year End | December |
| Full Time Employees | 517 |
Highlights
| Analyst Target | 32.00 |
| Market Cap | 2,516,700,000 |
| EBITDA | -542,073,984 |
Financials
| Curr Year EPS Estimate | -2.99 |
| Next Quarter EPS Estimate | -0.77 |
| Return on Assets | -0.27 |
| Return on Equity | -0.44 |
| Earnings Per Share | -2.92 |
| Gross Profit | -420,660,000 |
| Quarterly Revenue Growth | -1 |
Valuation
| Price/Sales (Trailing 12 Mt.) | 3,643.65 |
| Price/Book (Most Recent Quarter) | 2.77 |
Earnings
Warren Buffett Only Has Couple Of Rules For People Who Want To Work For Him, But Here's One Habit He Particularly Detests
Buffett instructs Berkshire Hathaway employees to think like owners and report bad news immediately. He values long-term investments and integrity.
Trump attacks ABC News correspondent Mary Bruce in angry response to three sharp questions
NEW YORK (AP) — President Donald Trump denounced ABC News' Mary Bruce as a “terrible reporter” Tuesday and threatened the network's license to broadcast after she asked him three sharp questions at the White House.
"Tech Prophet" Who Predicted the iPhone Now Predicts... - Ad
George Gilder - who predicted the iPhone 17 years early and gave Reagan the first microchip - is making his boldest call yet. He says an American nanotech "super-convergence" could mint more millionaires than any event in recent memory. He's found 3 stocks set to benefit the most.
Marjorie Taylor Greene Buys Blue Chip Stock Near 52-Week Low
Marjorie Taylor Greene is known for buying multiple stocks at a time, based on recent disclosures. A new filing shows one stock bought in November.
Schwab: Half Of US Investors May Ditch Other Assets For ETFs — 4 Funds To Watch
Nearly half of ETF investors could go all-ETF within five years, Schwab says. Here's how they're building portfolios with funds like ITOT, BND, and XLK.
Gold Near $4,073. Copper Tight. This Drill Hit Came Just in Time. - Ad
Dual exposure to two surging metals, plus 17.91% CuEq over mineable width, and infrastructure on site - this is what juniors dream of. And the market is just starting to notice.
These are the 37 donors helping pay for Trump's $300 million White House ballroom
WASHINGTON (AP) — President Donald Trump says his $300 million White House ballroom will be paid for “100% by me and some friends of mine.”
Palantir, Kimberly-Clark, Hims & Hers, Navitas And Cipher Mining: Why These 5 Stocks Are On Investors' Radars Today
PLTR, KMB, HIMS, NVTS, CIFR were among the stocks seen trending among investors on Monday, Nov. 3, 2025.
Metals... Not Missles... Is the New Arms Race - Ad
China and Russia control 70% of the world's critical minerals, giving them leverage over the West. One N. American discovery could help shift that balance by developing the metals essential for defense systems.
Cathie Wood Confirms $1 Million Bitcoin Price Target Despite Market Volatility
Cathie Wood, CEO of ARK Invest, remains confident in Bitcoin‘s (CRYPTO: BTC) future, even in the face of market volatility.
Sawyer Merritt Threatens To Move Assets If Charles Schwab Votes Against Elon Musk's Tesla Pay Package: 'I Can't In Good Conscience...'
Sawyer Merritt criticizes Charles Schwab for voting against Musk's $1 trillion pay package, threatening to move assets.
Trump Signs Law to Launch Dollar 2.0 - Ad
Trump just signed law S.1582, unleashing the biggest money shift in 100+ years. For the first time since 1913, private firms - not the Fed - can mint a "Dollar 2.0." Treasury says it could drain $6.6T from banks and pay 10X current savings rates. Early investors in minting firms could see 40X returns by 2032.
Apple Beats Earnings, $1 Billion Google AI Deal, Budget Mac And More: This Week In Appleverse
Apple had a busy week with earnings beats, AI partnerships, new product plans, and reflections on Steve Jobs' legacy.
Peter Schiff Says Bitcoin At $100K Is 'Incredible Opportunity' That Must Not Be Missed: 'If You Own Bitcoin, Hurry And…'
Peter Schiff, a vocal critic of the top cryptocurrency, has weighed in on Bitcoin (CRYPTO: BTC) reaching the $100,000 mark.
This Is the Type of Drill Hole That Changes Everything - Ad
A 19.5 metre zone returned 6.93% CuEq with a core 6.3 metre interval at 17.91%. The structure is bigger, richer, and more gold-loaded than expected. Drilling is active, and majors are watching.
Typhoon Kalmaegi leaves 26 dead in Philippines, people trapped on roofs and cars submerged
MANILA, Philippines (AP) — Typhoon Kalmaegi has left at least 26 people dead in the Philippines, mostly in flooding set off by the storm, which barreled across the central part of the country on Tuesday, disaster response officials said. Floodwaters trapped scores of people on their roofs and submerged cars.
McDonald's Q3 Preview: Report Shows Visitor Slump — Can Value Meals, Monopoly Help Guidance?
McDonald's may have seen a drop in visitors during the third quarter, according to a new report. Here's why investors may be more excited about Q4.
Elon's $25 Trillion Confession - Ad
Elon Musk: "Tesla will become a $25 trillion company." That would make Tesla 8x bigger than Apple today. How is that possible? He admits it's all thanks to this one AI breakthrough that will take AI out of our computer screens and manifest a 250x boom here in the real world.
Why Is Phio Pharmaceuticals Stock Soaring Today?
Shares of Phio Pharmaceuticals Corp. (NASDAQ: PHIO) are rising Monday after the company provided an update on an ongoing medical trial.
Qatar Airways to sell its holdings in Hong Kong's Cathay Pacific for $896 million
DUBAI, United Arab Emirates (AP) — Qatar Airways will sell its stake in Hong Kong-based Cathay Pacific Airways in a share buyback valued at $896 million, the companies announced, ending the Qatari carrier's .
Copper Over 13%. Gold Over 5 g/t. Same Hole. - Ad
This is not your average drill result. The copper-gold system just revealed a zone that rivals top-tier VMS discoveries. With over 3M insider shares recently bought, momentum is building.
African Union Rejects Trump's Claims Of Targeted Killings In Nigeria, Warns Against Military Action
The African Union rejected U.S. claims that Nigeria targets Christians, emphasizing the country's constitutional religious freedom and sovereignty.
Zohran Mamdani's Historic Victory Earns Him Congratulations From Bill Ackman, Bernie Sanders — Trump Wasn't 'On The Ballot,' Says President
Democrats win high-profile races despite Trump's absence and shutdown. Zohran Mamdani elected NYC mayor, Abigail Spanberger wins VA governorship, Mikie Sherrill flips NJ.
The Market Just Crossed a Dangerous Line - Ad
The man who predicted the 2008 crash and 2020 says today's soaring markets are NOT a bubble - they're something far stranger and more dangerous. He says it's about to change everything you know about money.
Zohran Mamdani Was Crypto Bettors' Overwhelming Favorite For New York City Mayor At 100% Odds — And He Just Won
Zohran Mamdani won the high-stakes New York City mayoral race Tuesday, a victory widely anticipated by cryptocurrency bettors, who had overwhelmingly backed the Democratic Socialist.
Trump may become the face of economic discontent, a year after such worries helped him win big
WASHINGTON (AP) — President got a serious that he’s out of touch with their fears about a deteriorating U.S. economy.
Congress to Feature Trump on $100 Bill? - Ad
A shocking new plan was just introduced in Washington; to celebrate Trump's new "golden age" by placing him on the $100 bill. In the months ahead, this former Presidential Advisor predicts the government will release a massive multi-trillion-dollar asset which it has held back for more than a century.
Taylor Swift, Elon Musk, Donald Trump, MrBeast — Robinhood Just Made Their Mojo Tradable
Robinhood has new prediction markets for its customers, with a focus on the entertainment sector. Here are some of the new markets.
Trump's Tariffs Face Doubts In Supreme Court: 'Major Questions Doctrine' Looms Large Amid Debate Over President's Emergency Powers
The U.S. Supreme Court raised doubts regarding President Donald Trump's authority to impose sweeping tariffs using a decades-old emergency powers law.
America's Defense Future Starts Underground - Ad
A N. American metals project just caught the attention of Rio Tinto - a mining giant. With four projects in key regions, this firm is aligned with Washington's push to rebuild the defense-metal supply chain.
Trump Barred From Deploying Oregon National Guard To Portland, Judge Cites State Sovereignty
A federal judge handed down a decisive ruling on Friday, blocking Trump's attempt to send Oregon's National Guard to Portland.
Bill Gates' Daughter Phoebe's AI Shopping Assistant Found Collecting Extensive User Data: Report
Phia, co-founded by Phoebe Gates, has been found collecting extensive user data through its browser extension, raising privacy concerns.
"Tech Prophet" Who Predicted the iPhone Now Predicts... - Ad
George Gilder - who predicted the iPhone 17 years early and gave Reagan the first microchip - is making his boldest call yet. He says an American nanotech "super-convergence" could mint more millionaires than any event in recent memory. He's found 3 stocks set to benefit the most.
Trump Says He Knows 'Very Little' About 'Huge' Crypto Industry, But Glad His Sons Are Involved
President Donald Trump expressed strong support for the cryptocurrency industry in an interview aired Sunday, stating that under his administration, the U.S. has emerged as the global leader in the sector.
Why Did MediciNova Stock (MNOV) Jump Over 87% In After-Hours Trading?
MediciNova shares soared over 87% in after-hours trading on Thursday following the publication of promising research.
Gold Near $4,073. Copper Tight. This Drill Hit Came Just in Time. - Ad
Dual exposure to two surging metals, plus 17.91% CuEq over mineable width, and infrastructure on site - this is what juniors dream of. And the market is just starting to notice.
Pfizer Clinches $10 Billion Deal To Buy Obesity Drug Maker Metsera, Outbidding Novo Nordisk In Fierce Battle For Weight-Loss Market Dominance
Nvidia CEO Jensen Huang cautioned Elon Musk against underestimating the challenges of semiconductor manufacturing, saying building a chip fab like TSMC's is "extremely hard."
Nasdaq Surges Over 100 Points, Records Gains In October: Greed Index Remains In 'Fear' Zone
CNN Money Fear and Greed index remained in Fear zone on Friday. US stocks closed higher, Nasdaq up 4.7% in October. Amazon reported earnings.
Metals... Not Missles... Is the New Arms Race - Ad
China and Russia control 70% of the world's critical minerals, giving them leverage over the West. One N. American discovery could help shift that balance by developing the metals essential for defense systems.
Ferrari CEO Confirms Electric Car Plans, Raises Full-Year Outlook
Ferrari N.V. stock rose after reporting Q3 results and guidance. Sales grew 7.4% and EPS beat estimates. Net revenues and adjusted EPS outlook raised.
Information, charts or examples are for illustration and educational purposes only and not for individualized investment management This message contains commercial elements, such as advertising. We only send these offers to those who have opted in to our newsletter. Past performance is not indicative of future results. For these reasons we strongly suggest trading in a DEMO/Simulated account. The information provided by us is for educational and informational purposes only. We make no representations or warranties concerning the products, practices or procedures of any company or entity mentioned or recommended and have not determined if the statements and opinions of the advertiser are accurate, correct or truthful. If you use, act upon or make decisions in reliance on information contained or any external source linked within it, you do so at your own peril and agree to hold us, our officers, directors, shareholders, affiliates and agents without fault.