The $43B Big Pharma Story is Starting Over-With a New Player
Big Pharma once paid $43B for a small biotech with a similar platform. Now, a new company is following that same playbook, leveraging its patented delivery technology to attract partnerships and near-term revenue potential.
Shares Stats
| Shares Outstanding | 88,040,000 |
| Shares Float | 60,780,000 |
| Shares Short | 1,620,000 |
| Insider Holdings | 3801% |
| Institution Holdings | 24.85% |
About AC Immune SA
AC Immune SA, a clinical stage biopharmaceutical company, discovers, designs, and develops medicines, and therapeutic and diagnostic products for the prevention and treatment of neurodegenerative diseases associated with protein misfolding. The company's SupraAntigen and Morphomer platforms are designed to generate biologics and small molecules, which selectively interact with misfolded proteins that are common in a range of neurodegenerative diseases. It develops Crenezumab, a humanized, conformation specific monoclonal antibody used to slow Alzheimer's disease (AD) progression; and Semorinemab, an investigational monoclonal anti Tau antibody that targets the N-terminal portion of the Tau protein and is designed to bind to Tau and slow its spread between neurons for the treatment of AD. The company is also developing ACI-24.060 for the treatment of down syndrome related AD; ACI-7104.056 to treat Parkinson's disease; and ACI-35.030, designs to stimulate a patient's immune system to produce antibodies against pathological phosphorylated Tau. In addition, it develops diagnostic programs consisting of PI-2620, a Tau diagnostic for AD, as well as non-AD Tauopathies; and ACI-12589, a-sync PET tracer that supports the differential diagnosis of multiple system atrophy from other neurodegenerative disease. Further, the company is researching and developing Morphomer Tau aggregation inhibitors to evaluate candidates in AD; Morphomer a-syn to compete with small molecule inhibitors of a-syn aggregation; and NeuroOrphan Tauopathies. Additionally, it generates discovery and preclinical stage molecules targeting range of neurodegenerative diseases, which include diagnostics targeting TDP-43, alpha-synuclein, and NLRP3. The company has license agreements and collaborations with Genentech, Inc.; Janssen Pharmaceuticals, Inc.; Life Molecular Imaging SA; and Eli Lilly and Company. AC Immune SA was incorporated in 2003 and is headquartered in Lausanne, Switzerland.
General
| Name | AC Immune SA |
| Ticker | ACIU |
| Exchange | NASDAQ |
| Sector | Healthcare |
| Industry | Biotechnology |
| Currency | USD |
| Country | USA |
| Fiscal Year End | December |
| Full Time Employees | 133 |
Highlights
| Analyst Target | 9.04 |
| Market Cap | 274,100,000 |
| EBITDA | -71,652,000 |
Financials
| Curr Year EPS Estimate | -0.69 |
| Next Quarter EPS Estimate | -0.17 |
| Profit Margin | -1642.99% |
| Operating Margin | -1,667.53 |
| Return on Assets | -0.22 |
| Return on Equity | -0.75 |
| Revenue | 5.2M |
| Earnings Per Share | -0.90 |
| Revenue Per Share | 0.04 |
| Gross Profit | -57,226,000 |
| Quarterly Revenue Growth | -0.96 |
Valuation
| Forward PE | 11.24 |
| Price/Sales (Trailing 12 Mt.) | 63.74 |
| Price/Book (Most Recent Quarter) | 3.87 |
Earnings
Marjorie Taylor Greene Goes Bargain Shopping, Discloses Buying These Two Stocks At 52-Week Lows
Congresswoman Marjorie Taylor Greene disclosed some new stocks recently. Unlike past trades in 2024 and 2025, the latest disclosure is rather unique.
Cathie Wood Dumps $11.6 Million Worth Of Tesla Stock: Here Is What Ark Purchased Instead
On Wednesday, Cathie Wood-led Ark Invest made significant trades involving Tesla Inc. (NASDAQ:TSLA), Coinbase Global Inc.
Trump Signs Law to Launch Dollar 2.0 - Ad
Trump just signed law S.1582, unleashing the biggest money shift in 100+ years. For the first time since 1913, private firms - not the Fed - can mint a "Dollar 2.0." Treasury says it could drain $6.6T from banks and pay 10X current savings rates. Early investors in minting firms could see 40X returns by 2032.
Joan Branson, wife of British billionaire Richard Branson, dies at 80
Joan Branson, the wife of British billionaire Richard Branson, has died at age 80.
Trump-Pardoned Ponzi Schemer Faces 37-Year Sentence For $44 Million COVID Scam
A previously convicted Ponzi schemer who had received a pardon from President Trump is heading back to prison due to involvement in a new fraudulent scheme.
Weiss Gold Veteran Makes Shocking New Call - Ad
Weiss expert Sean Brodrick went out on a limb last year and declared a historic event would send the yellow metal to $3,150. People laughed at him at the time, but he was off by just two days. Now, Sean has a shocking new prediction for gold ... and reveals a little-known way to get ahead of this bull market.
Bitcoin, Ethereum, Dogecoin Dip, While XRP Ticks Up: Analyst Assumes BTC Will Test New Lows In Upcoming Week
Leading cryptocurrencies inched lower on Sunday as investors maintained a subdued risk appetite.
California revokes 17,000 driver's licenses. But the state disputes it is over immigration concerns
California plans to revoke 17,000 commercial driver’s licenses given to immigrants after the Trump administration raised concerns about people in the country illegally receiving licenses to drive a semitruck or a bus. But Gov. Gavin Newsom said that isn't the reason.
Copper Is Tight, Silver Is Rising - And This Early Nevada Play Hits the Timing Perfectly - Ad
AI, electrification, battery storage, and data centers are pushing copper and silver demand sharply higher, even as supply stays tight. This region in Nevada offers rare multi-metal potential, and a new company has secured land in a district the surging district. It's one of the cleanest timing setups in the sector right now.
(Micro)Strategy's Structural Reset: Why Markets Are Repricing MSTR Beyond Bitcoin
The recent decline in Strategy's (NASDAQ:MSTR) stock price is not a simple pullback, nor is it a reaction driven by short-term sentiment. What is unfolding around MSTR is a broad structural repricing.
Airbus Orders Emergency Recall Of 6,000 A320 Jets After JetBlue Incident, Triggering Global Flight Delays And Holiday Travel Chaos
Airbus SE (OTC: EADSF) ordered immediate repairs to A320-family aircraft on Friday, recalling 6,000 jets after a recent JetBlue incident.
The Next Biggest Bull Run In Over 50 Years - Ad
Gold has hit all-time highs, breaking $4,000 an ounce - but history shows it could be on the verge of its biggest bull run in over half a century... triggered by a likely major event, eerily similar to what happened in the 1970s. (It's NOT inflation or anything you're likely expecting.) Now, a top analyst says you can capture ALL of the upside without touching a risky miner or a boring exchange-traded fund. He sees extraordinary potential gains long term with very little risk.
All 14 victims identified from fiery UPS cargo plane crash in Louisville
LOUISVILLE, Ky. (AP) — A grandfather and his young granddaughter. An electrician with two young children. A woman standing in line at a scrap metal business.
Trump's $2,000 Tariff Dividend Stumbles On Math: Cost Far Exceeds Revenue
Trump's $2,000 tariff rebate plan faces a major math gap, with estimated costs up to $606.8B—far exceeding tariff revenues in 2025 and 2026, says the Tax Foundation.
Legally "Skim" $6,361 Into Your Account? - Ad
A former hedge fund manager is now sharing his "Skim Codes" with regular people. They're not stocks. They're not crypto. They're 18-character codes designed to profit from recent market conditions. All you have to do is punch them into an ordinary brokerage account. 84% of these codes have given people the chance to generate cash payouts so far... and his next code is going out any day now.
What to know about the apartment tower fire in Hong Kong
HONG KONG (AP) — Hong Kong firefighters were making a final push to try and find any survivors from the city's , going apartment-to-apartment in the high-rise complex in an exhaustive search.
Ukrainian Naval Drones Cripple Two Russian Oil Tankers In Black Sea, Disrupt Moscow's Shadow‑Fleet Operations
Ukrainian naval drones struck 2 sanctioned tankers in Black Sea, critically damaging both and crippling a key Russian oil‑transport route.
First Drug to Show Breakthrough Myocarditis Data. Analysts See Potential 7-10x Upside. - Ad
This biotech just delivered a medical first in myocarditis and has a Phase 3 trial fully funded into 2027. Wall Street targets imply massive revaluation ahead.
Bill Gates' Daughter Phoebe's AI Shopping Assistant Found Collecting Extensive User Data: Report
Phia, co-founded by Phoebe Gates, has been found collecting extensive user data through its browser extension, raising privacy concerns.
Viking CEO Credits Strong Bookings To Resilient Customer Base Hungry For Travel
Viking Holdings Ltd. (NYSE: VIK) traded higher after beating expectations in third-quarter 2025 results, with strong revenue
Investing Legend Hints the End May Be Near for These 3 Iconic Stocks - Ad
Futurist Eric Fry say Amazon, Tesla and Nvidia are all on the verge of major disruption. To help protect anyone with money invested in them, he's sharing three exciting stocks to replace them with. He gives away the names and tickers completely free in his brand-new "Sell This, Buy That" broadcast.
Canada's prime minister and Alberta's premier sign pipeline deal that could reverse oil tanker ban
TORONTO (AP) — and the premier of Canada’s oil rich province of Alberta agreed Thursday to work toward building a pipeline to the Pacific Coast to diversify the country’s oil exports beyond the United States, in a move that has caused turmoil in Carney's inner circle.
Meta Allegedly Concealed Evidence Of Social Media Harm, According To Court Filings: Report
Meta Platforms Inc. allegedly hid evidence of social media harm by shutting down a study on Facebook and Instagram's impact on mental health.
The Smart Money Copper Trade - Ad
Quebec discovery. Strong grades. Roads and hydro in place. Funding secured for a busy drill calendar. Each assay can build scale and tighten the window for early entries as EVs and data centers pull harder on copper. Do not wait.
Jeff Bezos Says Almost Everyone Focuses On What The Next 10 Years Will Look Like—Here's What People Should Ask Instead
Amazon's latest surge in AWS growth and AI focus suggests that Jeff Bezos' long-standing philosophy of building around unchanging customer needs is continuing to shape the company's success more than a decade later.
Christmas market in Germany opens after last year's deadly attack in the city of Magdeburg
BERLIN (AP) — The Christmas market in the German city of Magdeburg opened Thursday, nearly a year after it was the scene of a horrific that left six people dead.
The Market Just Crossed a Dangerous Line - Ad
The man who predicted the 2008 crash and 2020 says today's soaring markets are NOT a bubble - they're something far stranger and more dangerous. He says it's about to change everything you know about money.
Cipher Mining Stock Pops As JPMorgan Moves To Overweight
Cipher Mining shares are rising Monday after JPMorgan upgraded the stock to Overweight and raised its price target to $18.
Trump Bars South Africa From 2026 G20 Summit In Florida, Freezes Aid Over 'White Genocide'
President Donald Trump directed that South Africa will not be invited to the 2026 G20 Summit in Miami, Florida. He also declared that all U.S. payments and subsidies to the country would be immediately suspended.
The $43B Big Pharma Story is Starting Over-With a New Player - Ad
Big Pharma once paid $43B for a small biotech with a similar platform. Now, a new company is following that same playbook, leveraging its patented delivery technology to attract partnerships and near-term revenue potential.
Eric Trump Lauds Bitcoin: 'Send $500 Million On A Sunday Night, Virtually No Fees'
Eric Trump has doubled down on his pro-crypto stance, promoting Bitcoin (CRYPTO: BTC) as a fix for inefficiencies in traditional finance and calling i
Adam Schiff Warns Trump Is Dragging America Toward A Venezuela War, Slams GOP For Treating Congress Like An 'Unnecessary Appendage'
Schiff warns that Trump's approach to Venezuela could lead to conflict and Congress must assert its power before it's too late.
Trump Signs Law to Launch Dollar 2.0 - Ad
Trump just signed law S.1582, unleashing the biggest money shift in 100+ years. For the first time since 1913, private firms - not the Fed - can mint a "Dollar 2.0." Treasury says it could drain $6.6T from banks and pay 10X current savings rates. Early investors in minting firms could see 40X returns by 2032.
Trump Pressures Taiwan To Train US Workers As TSMC Struggles In Arizona: Report
The Trump administration is reportedly pressing Taiwan, including TSMC, to invest more in U.S. semiconductor manufacturing.
The Polish 'magicians of glass' who create Christmas baubles for clients worldwide
CZĘSTOCHOWA, Poland (AP) — If you could design a bauble for your own Christmas tree, what would it be — a teddy bear dressed as a ballerina, a hummingbird, or a crimson phoenix?
Weiss Gold Veteran Makes Shocking New Call - Ad
Weiss expert Sean Brodrick went out on a limb last year and declared a historic event would send the yellow metal to $3,150. People laughed at him at the time, but he was off by just two days. Now, Sean has a shocking new prediction for gold ... and reveals a little-known way to get ahead of this bull market.
Elizabeth Warren Warns Trump Making A 'Tremendous Mistake' By Selling Federal Student Loans To Wall Street: 'I'm Fighting Back'
Sen. Elizabeth Warren (D-Mass.) criticized President Donald Trump's plans to sell federal student loans to private companies, warning that the move could create windfall gains for Wall Street, at the expense of taxpayers and average working Americans.
US Debt Of $38 Trillion Now A 'National Security Crisis,' Warns Top Economist, Another Blames Political Polarization: 'Neither Party Is…'
Richard Haass, the president of the Council on Foreign Relations, and other economists have sounded the alarm about the U.S. national debt, stating that it poses a significant threat to the country's security and global standing.
Copper Is Tight, Silver Is Rising - And This Early Nevada Play Hits the Timing Perfectly - Ad
AI, electrification, battery storage, and data centers are pushing copper and silver demand sharply higher, even as supply stays tight. This region in Nevada offers rare multi-metal potential, and a new company has secured land in a district the surging district. It's one of the cleanest timing setups in the sector right now.
Nvidia, Palo Alto, Coreweave, Broadcom And AMD: Why These 5 Stocks Are On Investors' Radars Today
U.S. stocks advanced on Wednesday as Nvidia's results reignited enthusiasm for AI plays. The Nasdaq climbed 0.59% to 22,564.22.
Information, charts or examples are for illustration and educational purposes only and not for individualized investment management This message contains commercial elements, such as advertising. We only send these offers to those who have opted in to our newsletter. Past performance is not indicative of future results. For these reasons we strongly suggest trading in a DEMO/Simulated account. The information provided by us is for educational and informational purposes only. We make no representations or warranties concerning the products, practices or procedures of any company or entity mentioned or recommended and have not determined if the statements and opinions of the advertiser are accurate, correct or truthful. If you use, act upon or make decisions in reliance on information contained or any external source linked within it, you do so at your own peril and agree to hold us, our officers, directors, shareholders, affiliates and agents without fault.
