3 Top Marijuana Stocks Poised to Take Off in 2024

The demand for cannabis is growing on a global scale. With legalization and decriminalization happening all around the world, many analysts and investors believe that marijuana will be a growing industry in the next decade. Get the latest report on 3 pot stocks set to take off in 2024!

By clicking the link above you will automatically opt-in to receive emails from ActivaTrade

Vertex Pharma scientist talks about the long road to developing non-addictive painkillers

MATTHEW PERRONE
April 15, 2024

WASHINGTON (AP) -- For decades, patients seeking medication for pain have had two choices: over-the-counter drugs like aspirin or powerful prescription opioids like oxycodone.

Opioid prescriptions have plummeted over the last decade as doctors have become more attuned to the risks of addiction and misuse during the country's ongoing drug epidemic.

Vertex Pharmaceuticals recently reported positive results for a non-opioid painkiller, one of several medications the Boston-based drugmaker has been developing for various forms of pain. Patients taking the drug after surgery experienced more pain relief than those getting a placebo, although the drug didn't meet a secondary goal of outperforming treatment with an opioid.

The Associated Press spoke with Vertex's chief scientist Dr. David Altshuler about the company's research and development plans. The interview has been edited for length and clarity.

Q: Why is Vertex interested in new drugs for treating pain?

There is a great need for additional medicines to help people manage pain. There are medicines like Tylenol that are modestly effective but they're very well tolerated. And there's medicines such as opioids that are very effective but unfortunately have side effects, as well as addictive potential.

Identifying additional medicines that could be used for people who need more pain relief but don't want to take the risks of opioids would be helpful for society.

Q: How did you develop these drugs?

Vertex has been working on this for 20 years, and the insight that led to the medicines actually came from studies of people who had a rare condition where they are insensitive to pain. They can feel things, sense temperature, but do not feel pain. This was actually identified in a family of fire walkers who could walk on hot coals.

So scientists figured out that that condition was due to inherited differences in a particular protein that has a role in pain signaling-- so if you lack this function you don't feel pain. So we and many others have worked for decades to make a medicine that could recapitulate that naturally-occurring phenomenon.

Q: Why wouldn't these drugs carry the same addictive properties as opioids?

Addictive medicines typically work in the brain and they have side effects that aren't really separable from the reduction in pain, because they're the same thing. That's their mechanism of action. In our case, our goal is to make medicines that act in the periphery, not in the brain, so they wouldn't have the same potential risk.

Q: Tell me about the recent data you've reported?

We've reported three studies in people with acute pain -- things like surgery or an injury -- all three studies were positive, all three studies showed substantial reduction of pain of about 50%.

One of the secondary endpoints was superiority to the opioid and the drugs were not superior to the opioid that was used for comparison, they were similar in magnitude. But because opioids have so many safety and tolerability issues, a medicine that could have similar efficacy but does not have those challenges might be of interest to people in pain.

Q: Are you testing this approach in patients with long-term pain?

We also did a study of diabetic peripheral neuropathy, which is long-term pain caused when people with diabetes have damaged nerves. That was also a positive study that showed clinically meaningful reduction in pain. So based on that study, a phase 2 study, we're now planning for a phase 3 study.

Q: What comes next?

For acute pain we're preparing to file for FDA approval based on our data. For the longer-term pain, what's called neuropathic pain, it's earlier in the development stage but the data is encouraging so far. So we're continuing studies to determine if it's possible to apply for approval there.

Continue Reading...

Popular

Tesla Stock Is Rallying Tuesday: What's Going On?

Tesla has increased its 72 month loan rate (APR) in the U.S. from 0.99% to 1.99%, according to Benzinga Pro. The loan rates for 36, 48 and 60 month loan terms are still set at 0.99%.

Taylor Swift bill is signed into Minnesota law, boosting protections for online ticket buyers

MINNEAPOLIS (AP) — People buying tickets online for concerts, sporting events and other live events in Minnesota will be guaranteed more transparency and protection under a so-called Taylor Swift bill signed into law Tuesday by Gov. Tim Walz.

The Biggest Year in Crypto Is Here... Right Now - Ad

The LAST bull run in crypto handed out 4 and 5-figure returns... This time the odds are stacked even better in our favor. 19 Wall Street banks are pouring millions into crypto right now... Blackrock Financial has gone ALL IN and is already breaking records with their investment. $100 trillion in Wall Street money is just waiting to be deployed. The only thing missing... is you.

Curaleaf Reports Q1 2024 Revenue Of $339M, 48% Gross Margin Amid Strategic Global Expansion

Curaleaf Holdings, Inc. (OTC: CURLF), a leading international cannabis company, reported its financial results for the first quarter of 2024.

'Dogecoin Killer' Shiba Inu Burn Rate Spikes 800%, Crypto Market Rallies As Sentiment Soars And More: This Week In Cryptocurrency

The week was a rollercoaster ride for the cryptocurrency market. The crypto world was buzzing with news, from Shiba Inu’s surging burn rate to speculation of certain altcoins becoming irrelevant.

Elon's New A.I. Device is About to Shock the World - Ad

Using this device you see... Elon Musk just tested a new type of A.I. that according to Wired Magazine will usher in... "The next step in human evolution."

Elon Musk Shares Who He'd Want To Spend His Last Moments With In Response To Warren Buffett's Advice

Over the weekend, Elon Musk agreed with a sentiment shared by investment titan Warren Buffett about the importance of spending time with loved ones, despite their contrasting investment philosophies. 

Exposed: 3 Cent Crypto to Explode June 24th? - Ad

Chris Rowe, the man who spotted 44 different coins that have returned over 100%, is now making the biggest crypto call of his ENTIRE career.... Because a powerful crypto event will trigger on June 24th... Sending hundreds of tiny cryptos soaring 5X, 50X, even 100X -- in just days.

California moves closer to requiring new pollutant-warning labels for gas stoves

SACRAMENTO, Calif. (AP) — California could require all new gas stoves sold in the state to carry a label warning users about pollutants they can release that have been linked to respiratory illnesses.

"This Could Be Worth Even More Than A.I." - Ad

Whitney Tilson's nailed many of the most famous stocks of the last 25 years -- including Netflix, Amazon, and Apple. Now he's pounding the table on a new technology rolling out across America, which early estimates say could create more wealth than A.I., the personal computer, and the smartphone combined.

GameStop, AMC, Alibaba, Rivian, Tesla: Why These 5 Stocks Are On Investors' Radars Today

The major U.S. indices had a mixed performance on Monday. The Dow Jones Industrial Average fell by 0.2% to close at 39,431.51.

Stocks Falter As Fed Signals Need For Higher-For-Longer Rates; Uber Crashes, Energy Sector Loses Ground: What's Driving Wednesday's Market?

Wednesday witnessed a tempering of the bullish sentiment that had buoyed Wall Street in recent sessions, with major indices showing slight declines around midday trading in New York.

4 Cryptos Set to Outperform Bitcoin in 2024 - Ad

Chris Rowe, the man who spotted 44 different coins that have returned over 100%, is now making the biggest crypto call of his ENTIRE career.... Because a powerful crypto event will trigger on June 24th... Sending hundreds of tiny cryptos soaring 5X, 50X, even 100X -- in just days.

Red, yellow, green ... and white? Smarter vehicles could mean big changes for the traffic light

As cars and trucks get smarter and more connected, the humble lights that have controlled the flow of traffic for more than a century could also be on the cusp of a major transformation.

Breaking News: Elon Musk Invents New Type of A.I. - Ad

According to 30-year Silicon Valley and Wall Street veteran, Eric Fry... A man who picked 41 plays that jumped 1,000%+... Elon Musk is about to shock the world again with this new type of A.I.... Mining new millionaires in the process.

Top public relations executive at Chinese technology firm Baidu apologizes after sparking backlash

HONG KONG (AP) — A top public relations executive from Chinese technology firm Baidu apologized Thursday after she made comments in a series of videos that critics said glorified a culture of overwork.

Hedge Fund Legend Druckenmiller Shares His Top Secrets For 30% Returns

Legendary hedge fund manager Stanley Druckenmiller made right bets at the right time. He came to fame for earning Soros $10B overnight. Successful hedge fund, Duquesne Capital, boasts $10B fortune.

Senate Opens Door for Uranium Boom, Outlawing Russian Supply - Ad

Just days ago, Uncle Sam made the bold move to ban the importation of Russian Uranium. This could create a massive supply vacuum considering the US is the number one buyer of enriched Russian uranium.

Japanese game maker Sega Sammy sells resort to US fund

TOKYO (AP) — Sega Sammy is selling its resort complex Seagaia to Fortress Investment Group of the U.S., the Japanese entertainment company said Friday.

Where Buffett, Gates, and Bezos Are Investing Now - Ad

Billionaires are plowing millions of dollars into a new technology that early estimates say could generate more wealth than A.I. -- and determine the future of companies like Microsoft. The problem? Most investors have no idea it's happening, or how to profit on it. This expert just went public with all the details, including which stocks to jump on immediately.

Czech power company CEZ reports net profit of $592 million in Q1, up by a quarter year-on-year

PRAGUE (AP) — The Czech power company CEZ said Tuesday its net profit in the first quarter of the year reached 13.6 billion Czech crowns ($592 million), 2.7 billion up compared with the same period of the previous year.

The No. 1 Crypto of 2024 (Trading for Less Than 10 Cents) - Ad

25X Predicted For THIS Crypto -- Starting on June 24th, this tiny 3-cent crypto just partnered with one of the biggest companies in the world... Amazon. And one team of crypto experts has identified it as the most promising crypto of 2024. You can see all of the details surrounding the No. 1 Crypto of 2024 here.

Trump Vs. Biden: New Swing State Poll Reveals Winner, One Key 2024 Election Issue Could Influence Result (Updated)

A new 2024 election poll of swing state voters shows Donald Trump with a commanding lead. One key factor could be determining the race in these markets.

Why Hims & Hers Health Stock Is Rising Today

After the market close on Monday, Hims & Hers Health reported strong first-quarter results that included revenue of $278.2 million, representing a 46% increase from $190.8 million in the first quarter of 2023. The number beat analyst estimates of $270.382 million.

Stock Alert from the Man Who Bought Amazon in 1999 - Ad

He predicted the rise of the Internet... the financial crisis of 2008... and many of the most famous stocks of the last 25 years -- including Amazon, Apple, and Netflix, before they were household names. (So many of his predictions came true, CNBC nicknamed him "The Prophet."). Now, this Wall Street millionaire is telling folks, "Here's exactly where I'd be putting my money in 2024."

Spot Bitcoin ETFs See $100M Inflows On Wednesday Amid Institutional Adoption

Bitcoin spot exchange-traded funds (ETFs) continued to attract investor interest on May 14, with total net inflows into these funds reached $100.5 million, highlighting ongoing demand for direct exposure to Bitcoin (CRYPTO:

Why's Wall Street Pouring Money Into This Tiny Biotech? - Ad

This biotech currently has four drugs in mid to late-stage clinical trials. And any one that gets approved could send their share price skyrocketing. Institutional investors are taking notice...They more than doubled their stock purchases of the company in the final quarter of 2023...Do they know something you don't?

Schwazze's Q1 2024 Financial Results: Takes A Hit In Colorado, Overall Cannabis Sales Up By 9%

Medicine Man Technologies, Inc., operating as Schwazze (OTC: SHWZ), announced its financial results for the first quarter ended March 31, 2024.

5 Wall Street Legends Just Bought This One Stock - Ad

"If you're not at the table, you're on the menu," says former Goldman Sachs VP, Dr. David Eifrig.

Pro-Palestinian protesters demand endowment transparency. But it's proving not to be simple

MINNEAPOLIS (AP) — On college campuses across the country, a rallying cry of has been “ ! We will not stop, we will not rest.”

As 'Roaring Kitty' Returns, Here Are 3 ETFs To Leverage The 2024 Meme Stock Wave

Meme stocks, led by Keith Gill, have resurfaced on social media, causing GameStop's stock to surge by 74% and AMC's by 80%. ETFs like ARCA:STCE can capitalize on this trend.

What's the Big Thing Musk, Bezos and Tim Cook All Have in Common? - Ad

One of America's most controversial CEOs says, "A new form of money in America is making some people (including Elon Musk, Jeff Bezos, and 17 of America's 25 wealthiest individuals), rich. It has nothing to do with gold, bitcoin, or anything like that, but it's 100% legal. The problem? Few Americans have a real understanding of how it works.

There's bird flu in US dairy cows. Raw milk drinkers aren't deterred

Sales of raw milk appear to be on the rise, despite years of warnings about the health risks of drinking the unpasteurized products — and an outbreak of bird flu in dairy cows.

Trending Now

Information, charts or examples are for illustration and educational purposes only and not for individualized investment management This message contains commercial elements, such as advertising. We only send these offers to those who have opted in to our newsletter. Past performance is not indicative of future results. For these reasons we strongly suggest trading in a DEMO/Simulated account. The information provided by us is for educational and informational purposes only. We make no representations or warranties concerning the products, practices or procedures of any company or entity mentioned or recommended and have not determined if the statements and opinions of the advertiser are accurate, correct or truthful. If you use, act upon or make decisions in reliance on information contained or any external source linked within it, you do so at your own peril and agree to hold us, our officers, directors, shareholders, affiliates and agents without fault.

Copyright trendadvisor.net
Privacy Policy | Terms of Service